Discovery of Progesterone Receptor Agonists and Antagonists inspired by the Fungal Metabolite PF1092C
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چکیده
منابع مشابه
Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling
Major roadblocks to developing effective progesterone receptor (PR)-targeted therapies in breast cancer include the lack of highly-specific PR modulators, a poor understanding of the pro- or anti-tumorigenic networks for PR isoforms and ligands, and an incomplete understanding of the cross talk between PR and estrogen receptor (ER) signaling. Through genomic analyses of xenografts treated with ...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 2006
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.64.559